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    Artwork for The a16z Show
    Episode

    Why AI Agents Can Beat the Incumbents

    The a16z Show · Oct 2, 2026 · 1 h 00 min
    Episode page

    a16z’s Seema Amble and Elena Burger sit down with Lio co-founder and CEO Vladimir Keil to ask where AI-native startups have an advantage when incumbent software companies already own the customer, the data, and the system of record. Their answer comes down to the work that happens outside those systems. In procurement, a final price in an ERP can hide hundreds of emails, spreadsheets, supplier…

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