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    Cover of Empire of Pain

    Empire of Pain

    Patrick Radden Keefe, Ricard Gil · 2021

    NATIONAL BOOK CRITICS CIRCLE NOMINEE • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • NEW YORK TIMES BEST SELLER • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments.

    Biography & Memoir
    Open LibraryAmazon
    Stats for nerds
    14recommend
    16mentions
    15people
    2021–2026years
    88% recommend13% neutral

    Mentions per year

    202120222023202420252026

    What Hacker News says

    1. ioadkFeb 2026
      I love these kind of books, some recommendations:

      Tech-specific (more like Careless People):

      - Empire of AI: tells the story of how the massive AI labs started and became as big as they are with a focus on OpenAI, provides new insight into the coup that outed Altman a couple years ago

      - Number Go Up: digs into the crypto culture and scams with novel insight into Tether

      - Bad Blood: a classic about Theranos and Elizabeth Holmes and how far a technologically impossible startup can go

      - Super Pumped: about Uber and the dirty tactics they employed to stay ahead, also touches on the toxic culture that was propagated there

      - Money Men: about the criminal enterprise around Wirecard, hard to keep up with at times due to the focus on the FT investigation rather than the fraud but interesting anyway

      Finance-focused:

      - Barbarians at the Gate: a classic about the attempted takeover of RJR Nabisco (oreos and tobacco) by management and early PE firms, told from first hand accounts

      - Too Big Too Fail: similar in form to Barbarians but instead focused on the 08 collapse and the attempts by the government to save all the irresponsible banks, told in too much of a sympathetic way for me but interesting to see how things happened behind the scenes

      - All the Devils Are Here: on the other hand a very unsympathetic look into the 08 crisis, by the same authors as Smartest Guys in the Room

      Other:

      - The Smartest Guys in the Room: my favourite of them all, tells the story of Enron and their rise and incredible fall, basically a foundational text on how to do a financial crime (and not get away with it)

      - Chip War: very relevant look into the production of computer chips, highlights the reliance on only a few companies and the incredible costs involved

      - Empire of Pain: also a favourite, goes into the Sackler family and how they built Perdue Pharma and then proceeded to cause the devastating opioid epidemic

      - The Power Broker: a classic about Robert Moses who basically built half of New York at the expense of marginalised residents, it's very long so I'd recommend reading/listening along with the 99% invisible breakdown

      I've not read Character Limit so have added that to my "To Read" pile!

      thread
    2. sparklingmangoJun 2024
      Additionally, I recommend the book Empire of Pain for an excellent deep dive into the Sackler family and how they essentially created the opioid epidemic. You'll be infuriated as you read it.
      thread
    3. CaptainZappJun 2024
      +1

      An amazing read and I also highly recommend it

      https://en.wikipedia.org/wiki/Empire_of_Pain

      thread
    4. arthemOct 2023
      > I’ve only ever see Prozac as a part of a turn for the worse.

      You might be interested in the book "Empire of Pain: The Secret History of the Sackler Dynasty"[1] by Patrick Radden Keefe. Although it focuses on Oxycodone and other painkillers it touch on Prozac and other SSRI's. Quite the eye opener...

      [1]: https://en.wikipedia.org/wiki/Empire_of_Pain

      thread
    5. JimtheCoderAug 2023
      Obligatory book recommendation: Empire of Pain https://www.goodreads.com/book/show/43868109-empire-of-pain

      At the end, it goes a bit into how to bankruptcy and settlements were structured.

      This family cannot do anything that isn't super shady...

      thread
    6. jamincanDec 2022
      I discovered Patrick Radden Keefe's writing this past year, and loved his writing style enough to immediately pick up a second of his books.

      Say Nothing: A True Story of Murder and Memory in Northern Ireland

      Empire of Pain: The Secret History of the Sackler Dynasty

      I've also been listening to a lot of audiobooks and was really impressed by Rosamund Pike's reading of The Great Hunt by Robert Jordan (Book 2 of the Wheel of Time series) for Audible; enough that I'm waiting to listen to Book 3 to when her reading of it is released next summer.

      thread

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