Lifespan
"From an acclaimed Harvard professor and one of Time's most influential people, this paradigm-shifting book shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls readers to consider a future where aging can be treated. For decades, experts have believed that we are at the mercy of our genes, and that natural damage to our genes--the kind that inevitably happens as we get older--makes us become sick and grow old. But what if everything you think you know about aging is wrong? What if aging is a disease--and that disease is treatable? In Lifespan, one of the world's foremost experts on aging and genetics reveals a groundbreaking new theory that will forever change the way we think about why we age and what we can do about it. Aging isn't immutable; we can have far more control over it than we realize. This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs--many from Dr. David Sinclair's own lab--that demonstrate how we can slow down, or even reverse, the genetic clock. The key is activating newly discovered vitality genes--the decedents of an ancient survival circuit that is both the cause of aging and the key to reversing it. Dr.
Stats for nerds
18recommend
46mentions
41people
2019–2024years
43% recommend52% neutral4% critical
Mentions per year
What Hacker News says
- I would read "Lifespan" by David Sinclair, who used Shannon's information theory to model epigenetic changes that cause us to age. Fascinating read and goes to show how far reaching impacts a foundational mathematical theory can have.
- Dr. David Sinclair (who led this study) has a fascinating book about this topic. He discusses this result and many others from his team, and the theory of epigenetics.
Lifespan (2019) by David Sinclair.
Also he narrates the audiobook, and he has a very suave and calming voice.
- Peter Attia [1] has a great podcast about many aging/healthspan issues. I listen to the free version but there is also a paid version of the podcast with more info.
The book Lifespan [2] from David Sinclair is also a fantastic source. Finally, if you can wade through some of the questionable statements and claims, the book The Longevity Paradox [3] from Steven Gundry does have some useful info.
[1] https://peterattiamd.com/ [2] https://www.amazon.com/Lifespan-Why-Age_and-Dont-Have/dp/150... [3] https://www.amazon.com/Longevity-Paradox-Young-Ripe-Plant/dp...
- For anyone interested in the topic, I'd encourage reading "Lifespan" by David A. Sinclair. As someone with little to no-knowledge about aging (other than feeling the effects of aging on myself) I found it very instructive on how our aging clock works and what are some of the ongoing studies to slow down or revert aging.
- David Sinclair's "Lifespan" Podcast changed my relation to food (although I can't vouch for scientific accuracy).
- Lifespan by David Sinclair would be my recommendation if you want to energise someone for molecular biology/ biotech
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