Fantastic voyage

What Hacker News says

1. wallaweOct 2011
   You may have heard of Ray Kurzweil, who's very involved with the singularity theory of technology. I read a book of his that is co-authored with Dr. Terry Grossman called "Fantastic Voyage." If you take the time to read this book, it gives many eating choices along with supplement suggestions for excellent mental and physical health. It's definitely worth the read.
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2. adrianscottJan 2011
   I would encourage you to read further on nutrition, particularly in books like Grossman and Kurzweil's books (Fantastic Voyage and Transcend), as well as Tim Ferriss's 4Hr body (which discusses a case of someone losing weight by changing the timing of their food consumption).

   Not all calories are equal.

   Starting off the day with a good breakfast can jumpstart the metabolism.

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3. queensnakeMar 2010
   There're also: Huperzine-A, Vinpocetine, Phosphatidyl Serine, Phosphatidyl Choline, Ginko, Acetyl-L-Carnitine, Taurine, Magnesium. There's a list of them in the book 'The Brain Trust Program', also Ray Kurzweil's 'Fantastic Voyage'.
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4. maximumwageJul 2008
   I liked "Fantastic Voyage: Live Long Enough to Live Forever" by Ray Kurzweil. Arthur De Vany's evolutionary fitness essay is also very good: www.arthurdevany.com/webstuff/RevisedEssay.pdf
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5. queensnakeSep 2007
   His bit about sugar, and feeling better - that's become more accepted, that sugar is just bad for you. We didn't evolve with so much of it. It does bad things hormonally over the long run. See Kurzweil's 'Fantastic Voyage' or Shallenberger's 'Diabetes Breakthrough' for specifics.
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6. jodrellblankDec 2022
   I have read Eliezer Yudkowsky's arguments in favour of longevity, and almost linked them myself. A few of them I can get behind - if there was no death, would we invent it? Probably not. But the cryonics ones I really can't agree with at all. Here in the UK we have a Conservative Prime Minister, a multi-millionaire who, together with his wife, is in the top 250 richest people in the country. And we have nurses, postal workers, transport workers, and more striking for more pay in the wake of the rising living costs, rising inflation, and energy price hikes (hikes which have lead to record profits for energy companies). The Prime Minister recently said that striking workers are "tired of being "foot soldiers" in the union's "class war"".

   That's the kind of out of touch that E Yudkowsky's writing has, from his position of employing someone to sit next to him to remind him he's supposed to be writing Harry Potter fan fiction instead of procrastinating. Quite possibly I would agree more if I was a genius academic able to write about anything that interested me for a living and had an audience hanging on my every blog post. Here for example[1] is a LessWrong post from Gwern which I resonate more with. Quotes: "Next to life itself, freedom is the most precious value; and most people’s lives are functionally devoid of it. Many cryonicists fail to see this, because they are self employed, are in jobs that offer them compensating satisfaction, or that they don’t perceive as “work”". and "Heaven isn’t waking up from cryopreservation and having to go into work two weeks later – FOREVER. That is the very definition of hell for most people."

   And even then it doesn't capture several things about cryonics arguments which bother me; the fiddling of the finances with insurance. Sure it may cost more than a normal person earns in a lifetime to cryopreserve someone, but if we handwave it away with "insurance" then it will all be fine. Insurance companies are scummy, the academic calculations about risk/reward/probability never take that real world fact into account, "markets are great" they say while everyday people are swindled by marketeers day in, day out. Or the delight in drastic medical treatments where the results may look good on paper, but look at people's lived experience of medical procedure aftermaths, problems they are left with, and it looks uncomfortably different. e.g. [2], c.f. how many doctors would personally refuse the old age treatments their elderly patients+families ask for. And then wonder what the actual lived experience of the cryo-revived would be, separate from the paperwork which says 'revived successfully'.

   And then how self-satisified the whole thing is, e.g. from the Gwern post: "many of the arguments that make cryonics credible, require a remarkable degree of both intelligence and scholarship. Inability to understand the enabling ideas and technologies usually means the inability to understand, let alone embrace, cryonics.". Now that alone wouldn't change how likely it is to work, but consider Eliezer Yudkowsky who values his own intelligence more than most things; he is overweight and under exercised[3]. Caloric restriction is the only proven way to extend life in any creatures, and it's much more likely that it is effective in humans than it is that you personally will be cryonically revived, but he doesn't do it. Why not? Exercise is about the only proven way to slow IQ decline with age, something you'd think he would value highly, and it appears he doesn't do that either. Why not?

   Compare with Ray Kurzweil and his book "the Fantastic Voyage - live long enough to live forever"[4], he has been partnering with a doctor for decades studying body biochemistry and interventions to improve his health and increase his life expectancy - and doing them - incredibly fiddly diet and micronutrient tracking and regular medical interventions at the doctor's office, dozens of regular blood tests. Seen through the lens of this book what it takes to try and live longer, makes it a bit less attractive to bother, doesn't it? Ray Kurzweil's reason was to live long enough to see the singularity in about 2035 and become immortal and revive his father. EY argues much more strongly for live extension than Ray Kurzweil, but apparently takes far less interest in doing anything about it today. The pro-cryonics arguments are often about how clever the cryonics suporters are for seeing a loophole in the universe - and conveniently it's a loophole that only needs an online signup with a credit card, but if you look at their 'revealed preferences', they aren't convinced enough to act on things which are much more likely to work but involve effort, so maybe agreeing with cryonics isn't about how intelligent you are, it's about how tempted you are to an easy low-effort fix?

   Compared to most creatures on Earth we already have longevity, btw. Imagine how much more you could master if you hadn't spent so long commuting, washing vegetables, making your bed, showering, gazing out the window, vacuuming dust-catcher carpets, polishing silverware ... if you surgically removed all your life, how much more life you could cram in. Oh you don't want to give up eating delicious calories for decades for the hope of a few more years at the end? Funny, me either. You don't want to spend hours exercising for the hope of a few more IQ points near the end? Weird, I don't either. You don't want to wash your vegetables in acid and drink only filtered water and spend hours a week analysing your blood test results making microadjustments to your dozens of regular nutritional supplements using the latest medical study results for guidance?[5] Hah, guess what, me either.

   [1] https://www.lesswrong.com/posts/mkrvsNi8cYGSjGqkh/on-the-unp...

   [2] https://collateral-damage.net/ read the Preview of Chapter One. The developing full story used to be there as blog posts before it was turned into a book, you might find them on https://web.archive.org/web/20081215144025/http://adventures...

   [3] https://live.staticflickr.com/6035/6262275090_186d29a15c_b.j... (belly)

   [4] http://www.fantastic-voyage.net/ and https://www.goodreads.com/book/show/83538.Fantastic_Voyage

   [5] Ray Kurzweil on supplements: "For boosting antioxidant levels and for general health, I take a comprehensive vitamin-and-mineral combination, alpha lipoic acid, coenzyme Q10, grapeseed extract, resveratrol, bilberry extract, lycopene, silymarin (milk thistle), conjugated linoleic acid, lecithin, evening primrose oil (omega-6 essential fatty acids), n-acetyl-cysteine, ginger, garlic, l-carnitine, pyridoxal-5-phosphate, and echinacea. I also take Chinese herbs prescribed by Dr. Glenn Rothfeld. For reducing insulin resistance and overcoming my type 2 diabetes, I take chromium, metformin (a powerful anti-aging medication that decreases insulin resistance and which we recommend everyone over 50 consider taking), and gymnema sylvestra. To improve LDL and HDL cholesterol levels, I take policosanol, gugulipid, plant sterols, niacin, oat bran, grapefruit powder, psyllium, lecithin, and Lipitor. To improve blood vessel health, I take arginine, trimethylglycine, and choline. To decrease blood viscosity, I take a daily baby aspirin and lumbrokinase, a natural anti-fibrinolytic agent. Although my CRP (the screening test for inflammation in the body) is very low, I reduce inflammation by taking EPA/DHA (omega-3 essential fatty acids) and curcumin. I have dramatically reduced my homocysteine level by taking folic acid, B6, and trimethylglycine (TMG), and intrinsic factor to improve methylation. I have a B12 shot once a week and take a daily B12 sublingual. Several of my intravenous therapies improve my body’s detoxification: weekly EDTA (for chelating heavy metals, a major source of aging) and monthly DMPS (to chelate mercury). I also take n-acetyl-l-carnitine orally. I take weekly intravenous vitamins and alpha lipoic acid to boost antioxidants. I do a weekly glutathione IV to boost liver health. Perhaps the most important intravenous therapy I do is a weekly phosphatidylcholine (PtC) IV, which rejuvenates all of the body’s tissues by restoring youthful cell membranes. I also take PtC orally each day, and I supplement my hormone levels with DHEA and testosterone. I take I-3-C (indole-3-carbinol), chrysin, nettle, ginger, and herbs to reduce conversion of testosterone into estrogen. I take a saw palmetto complex for prostate health. For stress management, I take l-theonine (the calming substance in green tea), beta sitosterol, phosphatidylserine, and green tea supplements, in addition to drinking 8 to 10 cups of green tea itself. At bedtime, to aid with sleep, I take GABA (a gentle, calming neuro-transmitter) and sublingual melatonin. For brain health, I take acetyl-l-carnitine, vinpocetine, phosphatidylserine, ginkgo biloba, glycerylphosphorylcholine, nextrutine, and quercetin. For eye health, I take lutein and bilberry extract. For skin health, I use an antioxidant skin cream on my face, neck, and hands each day. For digestive health, I take betaine HCL, pepsin, gentian root, peppermint, acidophilus bifodobacter, fructooligosaccharides, fish proteins, l-glutamine, and n-acetyl-d-glucosamine. To inhibit the creation of advanced glycosylated end products (AGEs), a key aging process, I take n-acetyl-carnitine, carnosine, alpha lipoic acid, and quercetin." - now that's longevity in practise, who's still interested? Who even bothered to read this, let alone do it?

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