Richard Jones, a physicist who writes about nanotechnology, the economics of innovation, and critiques of transhumanism.
HN commenters cite his Against Transhumanism book for arguments that nanotechnology won't bring super-abundance, and his views on molecular information processing.
Not really; or rather, I should say, the issue isn't nearly as clear-cut as some of the anti-nanotech groups that have been screaming about it would have you believe. They usually point to research by Ken Donaldson, showing similar pathogenic effects between asbestos and nanotubes longer than 20 μm, but fail to acknowledge that there's a difference between nanotubes (and graphene) in general and long nanotubes in particular, as Donaldson's study clearly points out. In brief:
> The basis of toxicity of asbestos and other fibrous materials is now reasonably well understood; their toxicity is based on the physical nature of the materials, rather than their chemical composition. In particular, fibres are expected to be toxic if they are long – longer than about 20 µm – and rigid. The mechanism of this pathogenicity is believed to be related to frustrated phagocytosis. Phagocytes are the cells whose job it is to engulf and destroy intruders – when they detect a foreign body like a fibre, they attempt to engulf it, but are unable to complete this process if the fibre is too long and rigid. Instead they release a burst of toxic products, which have no effect on the fibre but instead cause damage to the surrounding tissues. There is every reason to expect this mechanism to be active for nanotubes which are sufficiently long and rigid. [1]
Donaldson's research doesn't somehow negate the benefits--or even the possibility--of nanotubes; on the contrary, he's rather upbeat:
> There…
See chapter 3 ("Nanotechnology will not lead to super-abundance") of Against Transhumanism for a good argument for why this isn't so simple: http://www.softmachines.org/wordpress/wp-content/uploads/2016/01/Against_Transhumanism_1.0.pdf
Summary
1. Lack of rigidity, excessive stickiness of molecules (Van der Waals force), constant random interactions (Brownian motion) at the microscale of cells means mechanistic intuitions from the macroscale don't apply.
2. High surface area (combined with VdW force) causes problems related to friction and energy dissipation.
"The fundamental unit of biological information processing is the molecule, rather than any higher level structure like a neuron or a synapse; molecular level information processing evolved very early in the history of life."
http://www.softmachines.org/wordpress/?p=1558#more-1558