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    Artwork for Invest Like the Best with Patrick O'Shaughnessy
    Episode

    Alex Karnal - The Trillion-Dollar Health Revolution - [Invest Like the Best, EP.468]

    Invest Like the Best with Patrick O'Shaughnessy · Apr 21, 2026 · 1 h 32 min
    Episode page

    My guest today is Alex Karnal. Alex is the co-founder and managing partner of Braidwell, a life sciences investment firm he built after spending 15 years at Deerfield Management. The frame we use throughout the episode is the health stack. Alex talks about how most of the diseases that will claim most of our lives are already addressable with medicines that exist today. We work through the five…

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