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    Artwork for All-In with Chamath, Jason, Sacks & Friedberg
    Episode

    Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him

    All-In with Chamath, Jason, Sacks & Friedberg · Oct 12, 2026 · 25 min
    Episode page

    (0:00) Martin Shkreli joins the Besties! (0:55) Why quantum computing is a one-trick business and why he's betting against it (7:42) The drugs big pharma sells too cheap and his journey from hedge fund trader to pharma (11:37) AI, drug discovery, and who actually wins (21:32) Brilliance and rule-breaking, the gifted-kid trap & what prison taught him Thanks to our partners for making this…

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