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    Cover of Lehninger Principles of Biochemistry

    Lehninger Principles of Biochemistry

    David L. Nelson, Michael M. Cox · 2021

    "Available for the first time in Achieve, the definitive reference text for biochemistry Lehninger Principles of Biochemistry, 8e helps students focus on the most important aspects of biochemistry-- the principles! Dave Nelson, Michael Cox, and new co-author Aaron Hoskins identify the most important principles of biochemistry and direct student attention to these with icons and resources targeted to each principle."

    Biology & MedicinePhysics & Cosmology
    Open LibraryAmazon
    Stats for nerds
    4recommend
    6mentions
    6people
    2010–2023years
    67% recommend33% neutral

    Mentions per year

    20102012201420162018202020222023

    What Hacker News says

    1. jeejayFeb 2023
      Check Lehninger "Principles of Biochemistry". RuBisCo (most abundant enzyme in nature) fixates CO2 before they could be turned into sugars but this enzyme operates in suboptimal conditions at current CO2 concentrations. Thus increased CO2 concentration would improve crop yields.
      thread
    2. alextheparrotMay 2019
      I studied Biochemistry/Comp Sci and the foundational biochmeistry book imo is the Lehninger Principles of Biochemistry. It goes over the basic biochemistry and once you understand that things just start to “Make sense. Once you have those basics you can read the wikipedia article and things start to click.

      On the other hand, as a person who’s worked on sequencing software I’ve found the biochemistry knowledge to only be incidentally useful - though I may be underestimating some of the “basic” assumptions that were used day to day.

      thread
    3. thronemonkeyAug 2012
      The best textbooks for this (this is something of a consensus in the field also) are Molecular Biology of the Cell by Alberts et al. and Lehninger Principles of Biochemistry by Nelson and Cox.
      thread
    4. maxharrisSep 2010
      To really get the most you can out of the article, you might want to check out Lehninger Principles of Biochemistry, by Nelson and Cox. It's a wonderful book! Glycolysis is covered in chapter 14.
      thread
    5. JabavuAdamsJun 2021
      MIT 7.016 Introductory Biology, Fall 2018 https://www.youtube.com /playlist?list=PLUl4u3cNGP63LmSVIVzy584-ZbjbJ-Y63

      MIT 5.111 Principles of Chemical Science, Fall 2014 https://www.youtube.com/playlist?list=PLUl4u3cNGP63LOmB3_O0x...

      Textbooks (free PDFs available on gen.lib.rus.ec):

      Lehninger, Principles of Biochemistry https://www.macmillanlearning.com/college/ca/product/Lehning...

      Molecular Biology of the Cell https://www.ncbi.nlm.nih.gov/books/NBK21054/

      thread
    6. ghshephardJun 2011
      In the 1930s to 1950s, anything starchy was bad for you (Ask your grandmother) - In the 1950s - 1980s fat became the new evil. Then it was cholesterol, and saturated Fats. Then Transfatty Acids. For a small period of time there was a niche rebellion against all things carbs, and now it looks like we're coming back against refined sugars (or all things refined white)

      After reading a bit of anti-carb propaganda (Taubes) and being drawn into the "Wow, there are really bad things that you can eat" worldview - I decided to educate myself, and wget downloaded about 16,000 journal articles from the American Journal of Clinical Nutrition (They let you do this for $25, with the only request being that you put a 3 second delay between requests. Some awk/sed skills required to parse out the URLs, but not much. Totally download time was 39 hours)

      After reading through 40 or 50 of those articles on topics like "metabolism", "glycolysis", "diabetes", (btw - can anyone recommend a good PDF index tool - Lucene is really not easy to plug/play install - I ended up using recursive grep -il on the pdftotext versions to track down docs (very 1993) - but surely someone has solved the problem of indexing 16,000 PDFs in a directory - google fu did not yield much, surprisingly) - I realized that I needed to pick up more education.

      Two books I'm making my way through:

        o Essential Cell Biology, Second Edition - $7+shipping.[1]
        o Lehninger Principles of Biochemistry, Fourth Edition - $14+Shipping. [2]
       
      Plus, the one I really, really want - but used 2004 editions are insanely expensive, and there has been a lot of useful developments in nutrition and metabolism since 1999

        o Advanced Nutrition and Human Metabolism [3]
      
      Thank goodness for a generous "Amazon.com Look Inside" allowance - I've probably spent about 10+ Hours perusing this book.

      My takeaway, after admittedly putting only three or four months into this topic, is the following:

        o Very little has been donein the way of double-blinded,
          placebo controlled, rigorous nutrition studies.
      
        o The few that _have_ done these studies, have usually 
          come in with an agenda (Low Fat, Low Cholesterol, Low
          Carb).
      
        o For how important this whole field is, it's amazing 
          that we've invested so little.
      
      So yes - most cereal (the exception potentially being anything your Paleo ancestors would have recognized as cereal) is probably bad for you. I'll go farther than the OP and say you're probably kidding yourself if you think that "Corn Flakes" or "Crispy Crunch" is significantly better than "Fruit Loops" - it might be marginally better, but none of the refined stuff is doing great things for the western metabolism.

      [1] http://www.amazon.com/gp/product/081533480X

      [2] http://www.amazon.com/gp/product/0716743396

      [3] http://www.amazon.com/Advanced-Nutrition-Metabolism-Sareen-G...

      thread

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