
Zelazny manages to cleverly combine Jack (the Ripper), Sherlock Holmes, Dr. Frankenstein, and Dracula together with witches, werewolves, druids and many others in this amusing tale of an approaching confrontation that, on the Halloween of a full-moon, will change the cosmic balance of power between good and evil. Told through the eyes of Snuff, Jack's guard dog, who performs magical calculations in addition to accompanying his master on collecting expeditions into 19th century London. Twists and turns of magical espionage and adventure unfold as this unforgettable tale plays out over the course of 31 lonesome nights in October
That said, I do think book-level might be much more valuable. My first thought for this was Night in the Lonesome October by Roger Zelazny. I haven't read anything else by him yet because my brother informs me his other stuff is entirely different. Looking at Goodreads, I think that qualifies as far from his biggest hit. Is it "more profound?"? Doubtful, but seems likely that you shouldn't group it with his others. I want recommendations based on the book I like, not the author I mostly might-not.
A better example might be how Stephenie Meyer wrote the extremely popular Twilight books, and also The Host which is much less well-known, and better in many respects. Probably qualifies as more profound, too—it's told from the perspective of a parasitic alien. Picture the Yeerks from Animorphs if you read those.)
All worth reading, the last probably the least enduring.
