Drew McCormack and others write Mac scientific computing tutorials covering Cocoa, Grand Central Dispatch, OpenCL, and some Mac how-to posts.
HN links it for follow-up posts on Grand Central Dispatch with an OpenMP benchmark, plus Mac guides on running Dwarf Fortress and fixing the expired X3 certificate.
That's true - it may lack some advanced feature. But it's quite capable for the large majority of users. The only thing I don't like is that with newer macOS versions Lulu has dropped its own kernel extension in favour of macOS' built-in Network Extension framework that may have backdoor "bugs" built-in to allow Apple to spy on us (e.g. https://macresearch.org/mac-feature-bypass-firewalls-removed/?noamp=mobile ). I don't recall, but I think Little Snitch still uses it own custom kernel extension as macOS NEF doesn't still support all the features that LS offers.
They have been heavily involved in OpenCL for a while though, which is not tied to any specific graphics card manufacturer, or graphics cards specifically. There are some pretty nice OpenCL tutorials here btw: http://www.macresearch.org/opencl
Drew McCormack has already posted a follow-up that goes into greater detail, including a limited benchmark comparison to OpenMP.
http://www.macresearch.org/cocoa-scientists-xxxi-all-aboard-grand-central
You can run it on m1 under x86 wine via rosetta ("wineskin") [0].
Turtles all the way down!
0: https://macresearch.org/play-dwarf-fortress-mac/
My 2010 Macbook still works fine after I've updated the expired X3 certificate [0].
[0]: https://macresearch.org/dst-root-ca-x3-expired-mac/
http://www.macresearch.org/